![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]()
New York - January 2, 2002 A team of New York University researchers has taken a major step in building a more robust, controllable machine from DNA, the genetic material of all living organisms. Constructed from synthetic DNA molecules, the device improves upon previously developed nano-scale DNA devices because it allows for better-controlled movement within larger DNA constructs. The researchers say that the new device may help build the foundation for the development of sophisticated machines at a molecular scale, ultimately evolving to the development of nano-robots that might some day build new molecules, computer circuits or fight infectious diseases. The research team was led by NYU chemistry professor Nadrian C. Seeman. Their findings are reported in the January 3, 2002 issue of Nature. Professor Seeman said, "DNA devices can provide models for the development of nanorobotic applications -- provided the individual devices can be manipulated separately. Our findings have taken the first definitive step in localizing movement within molecular scale DNA machines, introducing independence of movement within a wider structure." Professor Seeman has led research teams to previous breakthroughs in the construction of structures and devices from DNA molecules. All of these structures use base pairing, which allows strands of DNA to be programmed to self-assemble in well-defined ways. In January 1999, Professor Seeman's lab announced the development of a machine constructed from DNA molecules, which had two rigid arms that could be rotated from fixed positions by adding a chemical to the solution. However, the chemical affected all molecules within a structure uniformly. The research team's most recent findings demonstrate how movement can be manipulated within molecule pairs without affecting others within a larger structure. This is done by inserting DNA "set" and "fuel" strands into individual molecule pairs. Scientists used paranemic crossover (PX) molecule pairs and produced a half-turn rotation by converting them into JX2 molecule pairs by removing the set strands with fuel strands and replacing them with new set strands that reconfigure the structure of the device. The data presented include both bulk measurements shown by gel electrophoresis and detection of individual structure changes by atomic force microscopy.
These findings are reported in a letter to Nature entitled "A Robust DNA Mechanical Device Controlled by Hybridization Topology." The authors are Hao Yan, Xiaoping Zhang, Zhiyong Shen and Nadrian C. Seeman. Community Email This Article Comment On This Article Related Links Ned Seeman's Laboratory SpaceDaily Search SpaceDaily Subscribe To SpaceDaily Express Space Technology News - Applications and Research
![]() ![]() Northrop Grumman Corporation has been selected to develop "military-grade," solid-state laser technology that is expected to pave the way for the U.S. military to incorporate high-energy laser systems across all services, including ships, manned and unmanned aircraft, and ground vehicles. |
![]() |
|
The content herein, unless otherwise known to be public domain, are Copyright 1995-2006 - SpaceDaily.AFP and UPI Wire Stories are copyright Agence France-Presse and United Press International. ESA PortalReports are copyright European Space Agency. All NASA sourced material is public domain. Additionalcopyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by SpaceDaily on any Web page published or hosted by SpaceDaily. Privacy Statement |